This document was first published as a pamphlet in 1967, shortly after possession of LSD was made illegal in the USA, by Lisa Bieberman. It is a guide for first-time experimenters with LSD, though anyone who uses psychedelics is sure to benefit from reading it. For more on author Lisa Bieberman, visit Erowid. Not much has changed in fifty years — I agree with almost all of her advice, but have amended it with a few of my own comments [in italicized brackets].
Effect Index serves as the platform for the Subjective Effect Index (SEI), a resource containing formalised documentation of the vast number of distinct subjective states that may occur under the influence of hallucinogens. We strive to comprehensively document and describe the wide variety of potential hallucinogenic experiences. The SEI is presented in an easily readable format that contains not only descriptions, but also image, video, and audio replications of these effects. We believe that in pioneering formalised subjective effect documentation, we may demystify the psychedelic experience. This has the potential to allow hallucinogen usage to become more culturally acceptable, better understood, and create a platform on top of which these substances may be more easily studied. Effect Index was initially founded as a side project on 30 June, 2017 by Josie Kins, the founder of PsychonautWiki and DisregardEverythingISay. It serves as a platform for content that has been in constant development for the previous six years on these sites. However, the aforementioned content is now hosted on its own dedicated platform with the hope of further spreading the documentation and creating a universal terminology set that gives people the vernacular to fully describe experiences that were previously considered ineffable.
Psychedelic Experience (PEx) is a comprehensive online resource for information surrounding psychedelic substances. We are a community based non-profit organization, created by and for psychedelic and plant medicine communities. Our mission is to support and facilitate global healing and personal growth through safe, responsible and legal use of plant medicines and psychedelic-assisted treatments. We are opposed to the commercialization of psychedelics and believe that profiteering and opportunism go against the very heart of the psychedelic experience. That’s why we are a non-profit and will never be driven by corporate interests or shareholder greed. Our website and global directory service of psychedelic-related organizations seeks to promote the safe, responsible use of psychedelics. We provide accurate, evidence-based information regarding retreat centers, facilitators, shamans, therapeutic modalities, and organizations.
Genus Salvia, commonly known as sage, is the largest genus in the Lamiaceae family. It comprises many species traditionally used as brain-enhancing tonics. In vitro and animal studies have confirmed that several Salvia species contain a large array of active compounds that may enhance cognitive activity and protect against neurodegenerative disease. In this review, the active constituents in plants belonging to the genus Salvia are summarised, and their influence on pharmacodynamics pertinent to cognitive activity are detailed. In particular, the effects of plants belonging to the genus Salvia and their constituents on cognitive skills including memory, attention and learning are detailed. Their potential effects in dementia, including Alzheimer’s disease, are also examined. Completed human trials are summarised, and factors influencing the potency of Salvia plants are covered. Finally, directions for future research are proposed to enhance our understanding of the potential health benefits of Salvia plants. Key Points Salvia plants and their constituents can influence several biological mechanisms associated with cognition including their effects on amyloid-β, cholinergic activity, neurotrophins, oxidative stress, inflammation and anxiolytic/antidepressant behaviours. Several studies have confirmed the many Salvia species have promising, cognitive-enhancing effects in human adults. Further research is required to examine the longer-term cognitive-enhancing effects of Salvia species on cognition, memory and the treatment of neurodegenerative diseases such as Alzheimer’s disease.
Before psychedelic therapy and services becomes widely available, there needs to be a better understanding of all the ways these experiences can go wrong.
After a half century spent waging war on drugs, Americans seem ready to sue for peace. The 2020 elections brought plenty of proof that voters have leapt ahead of politicians in recognizing both the failures of the drug war and the potential of certain illicit drugs as powerful tools for healing.
Research into psychedelics, shut down for decades, is now yielding exciting results.
LSA is an Ergine closely related to LSD, and Indigenous communities in Mexico have used it since immemorial times.
One of the most lasting and influential artistic movements of the 20th century was created with and for Black artists. Why has their contribution been so overlooked?